Optimizing Door-to-reperfusion Times of One-stop Management in Acute Ischemic Stroke (ORETOM)
Acute Ischemic Stroke
About this trial
This is an interventional treatment trial for Acute Ischemic Stroke focused on measuring acute ischemic stroke, angiosuite, reperfusion times, One-stop
Eligibility Criteria
Inclusion Criteria: Acute ischemic stroke in the anterior circulation caused by large vessel occlusion. National Institute of Health Stroke Scale (NIHSS) ≥10. Premorbid modified Rankin Scale (mRS) ≤ 2 Target Mismatch profile: CBF < 30% volume < 100ml, Mismatch volume ≥ 15 ml and Mismatch Ratio >1.8. Available angiosuite. CBF < 30% volume: 70 - 100 ml when non-contrast computed tomography (NCCT) Alberta Stroke Program Early Computed Tomography Scores (ASPECTS) was 3 - 5 and/or beyond 6 hours after symptom onset Exclusion Criteria: Evidence of intracranial tumors, the encephalitis, the hemorrhage: either an intracranial hemorrhage (ICH) or subarachnoid hemorrhage (SAH) by the biplane flat panel detector computed tomography. Participated in another studies. Loss to follow-up after discharge. A severe or fatal combined illness before acute stroke.
Sites / Locations
- Can Tho SIS Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Standard workflow (SW)
One-stop (OS)
Acute ischemic stroke caused by large vessel occlusion was diagnosed by Magnetic resonance imaging (MRI) and Magnetic resonance angiography (MRA) at admission in MRI room + Recanalization therapy in angiosuite
Acute ischemic stroke caused by large vessel occlusion was diagnosed + Recanalization therapy by the flat-detector computed tomography in angiosuite at the same time.