A Comprehensive Evaluation of Hyperbaric Oxygen Therapy in Resuscitation Medicine - A Pilot Study (HOT-RESUS 1 Trial) (HOT-RESUS 1)
Heart Arrest, Brain Injuries
About this trial
This is an interventional other trial for Heart Arrest
Eligibility Criteria
Depending on the study arm. ICU patients: Inclusion criteria: sustained ROSC since a maximum of 24 hours, hemodynamic and respiratory stable enough for transportation to HBOT. Exclusion criteria: traumatic CA, age <18 years, pregnancy, (tension-) pneumothorax. Healthy volunteers: Inclusion criteria: able to come to the study site themselves. Exclusion criteria: age <18 years, (suspected or desired) pregnancy, known chronic illnesses, especially known claustrophobia, history of CA, history of pneumothorax, acute or chronic ear / nose condition. CA survivors after hospital discharge: Inclusion criteria: history of CA from hospital discharge up to a maximum of 3 years ago, able to come to the study site themselves. Exclusion criteria: age <18 years, (suspected or desired) pregnancy, known claustrophobia, history of pneumothorax, acute or chronic ear / nose condition.
Sites / Locations
- Antwerp University HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Active Comparator
post-ROSC
cardiac arrest survivors discharged home receiving HBOT
healthy volunteers receiving HBOT
patients directly post-ROSC receiving HBOT
cardiac arrest survivors discharged home
healthy volunteers receiving HBOT