Nutraceutical Improvement of Glucose Metabolism, NAFLD and Insulin Resistance by Oat-fiber Supplementation in Type 2 Diabetes Mellitus Patients (NIMROD)
Type 2 Diabetes, NAFLD
About this trial
This is an interventional treatment trial for Type 2 Diabetes focused on measuring insoluble cereal fiber, insulin resistance, glucose tolerance, inflammation, incretins
Eligibility Criteria
Inclusion Criteria: type 2 diabetes mellitus HOMA-IR > 2.5 NAFLD (MR-S > 5,56 %) Exclusion Criteria: insulin treatment diabetes type 1, 3 or 4 severe cardiopulmonary, renal, inflammatory, gastrointestinal, psychiatric or endocrine disorder alcohol abuse or excess alcohol intake recent CVD event (< 3months) relevant liver disease other than NAFLD current cancer diagnosis or treatment allergy or incompatibility to the supplement
Sites / Locations
- Charite University Hospital BerlinRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Supplementation with insoluble cereal fiber
Supplementation with placebo
Drinking powder supplement providing 7,5 grams of insoluble fiber per sachet, taken twice daily over a period of 12 weeks without any changes in dietary behavior, caloric intake or physical activity
Drinking powder supplement providing no insoluble fiber, but maltodextrin, taken twice daily over a period of 12 weeks without any changes in dietary behavior, caloric intake or physical activity