A Study to Evaluate the Effiacy and Safety of HIP0612 in Patients With Gastric Ulcer
Gastric Ulcer
About this trial
This is an interventional treatment trial for Gastric Ulcer
Eligibility Criteria
Inclusion Criteria: 19 years to 75 years Diagnosis of active gastric ulcers according to the Sakita-Miwa classification from upper GI endoscopy Patients understood the consents and purpose of this trial and signed consent form Exclusion Criteria: Patients who cannot perform endoscopy Finding of malignancy, duodenal ulcer, ulcer perforation, postoperative (eg, endoscopic mucosal resection, endoscopic submucosal dissection) ulcer(s), Barrett's oesophagus measuring >3cm, oesophageal dysplasia, oesophageal and/or gastric varices, bleeding disorder on upper GI endoscopy History of definitive acid lowering surgery or pervious oesophageal or gastric surgery (except for benign tumor excisionn, simple close of perforations) Zollinger-Ellison syndrome, pyloric stenosis, oesophageal motility disorder, esophageal stricture Severe hepatic disease Severe renal disease, CKD Bleeding disorder History of malignancy or was treated for malignancy within 5 years before the start of the Visit 1 Patients who have taken drugs containing following list within 2 weeks prior to upper GI endoscopy, or requirement of persistent use of drugs during the study period: acid suppressive drugs, antacids, anticholinergic drugs, gastroprotective agent Patients who have taken drugs containing following list within 1 weeks prior to upper GI endoscopy, or requirement of persistent use of drugs during the study period: antithrombotic agents, NSAIDs, aspirin Requirement of use of excluded medications during the study History of allergic reaction to the medications used in this study Glucose-galactose malabsorption, Fructose intolerance, Sucrase-isomaltase deficiency Use of other investigational drugs within 30 days prior to the study History of alcohol or drug abuse Positive to pregnancy test, nursing mother, intention on pregnancy Considered by investigator as not appropriate to participate in the clinical study with other reason
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
HIP0612
RLD2204
Taking HIP0612+HPP2202 once daily for 4 or 8 weeks.
Taking RLD2204+HPP2201 once daily for 4 or 8 weeks.