Preoperative Supine Time for Adrenal Venous Sampling (PSTAVS)
Primary Aldosteronism
About this trial
This is an interventional treatment trial for Primary Aldosteronism focused on measuring adrenal venous sampling, preoperative supine time, primary aldosteronism, resistant hypertension
Eligibility Criteria
Inclusion Criteria: Patients are clinically diagnosed as primary aldosteronism with ARR≥37 (PAC showed as pg/ml, renin showed as μIU/mL) and passed through PA confirmatory tests (PAC-post CCT>110pg/ml, PAC-post SSIT >80pg/ml, or PAC-post FST>60pg/ml). PAC: plasma aldosterone concentration; Patients with willing for AVS; Age 18 or above, male or female, with legal capacity. Exclusion Criteria: Patients with suspected adrenocortical carcinoma or pheochromocytoma; Patients with high risk of adrenal surgery; Patients have been subtyping to glucocorticoid-suppressible hyperaldosteronism or familial hyperaldosteronism type III; Patients were diagnosed as Cushing syndrome or subclinical Cushing syndrome; Patients were treated with glucocorticoids recently; Patients with whole body or venipuncture area infection; Patients with venous access thrombosis; Patients are allergic to iodine; Patients with X-ray contraindications; Patients with coagulation dysfunction; Patients are unable to cooperate and follow-up.
Sites / Locations
- The second affiliated hospital of zhejiang university school of medicineRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
experimental group(15-min supine group)
control group(2-hour supine group)
Participants in the experimental group will keep supine position for 15 minutes before AVS.
Participants in the control group will keep supine position for 2 hours before AVS.