Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery (NOSE)
Pituitary Tumor
About this trial
This is an interventional supportive care trial for Pituitary Tumor
Eligibility Criteria
Inclusion criteria Adult patient undergoing endoscopic surgery for resection of pituitary tumors nonfunctioning adenoma acromegaly prolactinoma Rathke's cleft cyst Adults >18 and <85 years of age English speaking and able to understand the ASK Nasal-12 and SNOT-22 scales Free of any physical, mental, or medical condition which, in the opinion of the investigator, makes study participation inadvisable Planned binostril surgical approach Either with or without septal flap reconstruction Either with or without septoplasty Exclusion criteria Active sinus infection Allergic rhinitis Asthma Vascular or inflammatory disease History of previous sinonasal surgery Any subject who is unwilling or unable to sign informed consent for the study Pregnancy Incarcerated patients Cushing's disease History of chronic sinusitis Extended approaches to the skull base Active sinusitis Nasal polyps Concurrent antibiotics for another indication (i.e., urinary tract infection) Immunodeficiency History of radiation to the skull base
Sites / Locations
- Barrow Neurological Institute at St. Joseph's Hospital and Medical CenterRecruiting
- Cleveland ClinicRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
Nasal saline irrigation
No Intervention
Patients randomized to standard postoperative nasal care with twice a day saline sinonasal irrigations
Patients randomized to not performing saline sinonasal irrigations.