Move With Air: Physiological Response Assessment
Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease, Heart Failure
About this trial
This is an interventional treatment trial for Chronic Obstructive Pulmonary Disease focused on measuring Breathlessness, Dyspnea, Exercise, Fan-to-face therapy, Physiological Mechanisms, Constant work rate exercise
Eligibility Criteria
Inclusion Criteria: have a physician diagnosis of cardiopulmonary disease (e.g., chronic obstructive pulmonary disease, interstitial lung disease, heart failure) must report breathlessness on exertion, defined as modified Medical Research Council dyspnea scale rating ≥2 despite optimal treatment of their underlying cardiopulmonary pathophysiology according to established clinical practice guidelines have a body mass index of >18.5 kg/m2 and <35 kg/m2 must be cleared by a physician to perform physical activity/exercise following the completion of the 'Medical Clearance Form for Cardiopulmonary Exercise Testing'. Exclusion Criteria: have changed their respiratory or cardiac medication dosage and/or frequency of administration in preceding two weeks have had a disease exacerbation/hospitalization in preceding six weeks have important contraindication(s) to exercise (e.g., significant musculoskeletal or neurological disease) or pulmonary function testing (e.g., eye, chest or stomach surgery, or any history of coughing up significant amounts of blood in the previous 3 months).
Sites / Locations
- Centre of Innovative Medicine of the McGill University Health Centre
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Sham Comparator
No Intervention
Fan-to-face
Fan-to-leg
No fan
The participants will complete a 3-minute constant work rate treadmill test at 75% of peak power output achieved on an incremental treadmill test with a basic, portable fan placed in front of the face. The fan will be placed at a location to target the second and third branches of the trigeminal nerve and will be placed a distance so that the maximum airflow speed at the face is 4.3 meters/second.
The participants will complete a 3-minute constant work rate treadmill test at 75% of peak power output achieved on an incremental treadmill test with a basic, portable fan placed facing the side of the lower left leg (side calf area). The fan will be placed a distance so that the maximum airflow speed at the face is 4.3 meters/second.
The participants will complete a 3-minute constant work rate treadmill test at 75% of peak power achieved on an incremental treadmill test with no fan.