CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
Traumatic Brain Injury, Insomnia, Depression
About this trial
This is an interventional treatment trial for Traumatic Brain Injury focused on measuring Traumatic Brain Injury, Insomnia, Posttraumatic Stress Symptoms, Depression, Concussion, Head Injury, Brain Injury, Cognitive Behavioral Therapy for Insomnia, Mindfulness-based Treatment for Insomnia
Eligibility Criteria
Inclusion Criteria: Meet the Veterans Affairs Medical Center (VAMC) and Department of Defense (DoD) criteria for TBI Mild to moderate TBI severity at time of injury based on review of medical records Time duration since injury >3 weeks Endorse insomnia symptoms (Insomnia Severity Index [ISI] score > 9) Display sufficient cognitive capacity to provide informed consent (Montreal Cognitive Assessment (MoCA), Z-score > -2149) 18 years of age or greater Access to and ability and to use computer Exclusion Criteria: History of neurological diseases other than TBI and not attributable to TBI Known history of intellectual or developmental disability Communication difficulties or inability to speak English Sleep apnea [apnea hypopnea index (AHI) >15; individuals with mild apnea (AHI > 5 and <14.9) will be informed, but allowed to participate]. Patients who use a continuous positive airway pressure (CPAP) device for sleep apnea will be eligible for participation if they are below the apnea/hypopnea cutoff while using CPAP, are adherent to using the device (> 4 hours/night 21/30 consecutive days) and agree to continue using the device during study participation. Patients using psychotropic medications may be included if they are on a stable dosage for the last three weeks prior to the study.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Cognitive behavioral therapy for insomnia (CBT-I)
Mindfulness-based treatment for insomnia (MBTI)
CBT-I treatment will involve a standardized 6-session blended intervention that combines cognitive and behavioral techniques. The core components include (1) education about sleep and insomnia, stimulus control (SC) and sleep restriction (SRT) (week 1); (2) sleep hygiene education (week 2); and (3) relaxation training, cognitive restructuring (to counter-arousal and address sleep-interfering cognitions), adherence monitoring, and adjusting the recommended sleep-wake schedule (weeks 3 through 6). The final session will also include a review of treatment content and relapse prevention. Common to all sessions is an initial review of participant diary data, charting progress, setting measurable goals, discussing adherence, and reinforcing learned skills.
MBTI treatment will involve a standardized 6-session intervention which integrates the mindfulness training and exercises from mindfulness-based stress reduction (MBSR) with behavioral strategies based on sleep restriction therapy and stimulus control delivered within the context of mindfulness principles. Mindfulness principles include: 1) increase awareness of the mental and physical states that promote sleep (i.e., sleepiness), 2) shift sleep-related metacognitions to reduce hyperarousal, and 3) promote a mindful stance to respond when symptoms of insomnia arise. An overview of the treatment program, sleep education, and an introduction to the principles of mindfulness meditation is given (week 1). Then a combination of mindfulness meditations, sleep restriction, and stimulus control is conducted (week 2-6).