A Study Evaluating Safety, Tolerability, and Pharmacokinetics of QRL-101 in Healthy Participants
Healthy Volunteers

About this trial
This is an interventional treatment trial for Healthy Volunteers focused on measuring Healthy Volunteers
Eligibility Criteria
INCLUSION CRITERIA Age 18 to 70 years of age inclusive at the time of signing the informed consent. Clinical chemistry laboratory values within acceptable range for the population, as per investigator judgment. Body mass index of 18 to 32 kg/m2 (inclusive). Willing and able to practice effective contraception. EXCLUSION CRITERIA Currently enrolled in any other clinical trial involving a study drug or off-label use of a drug or device, or any other type of medical research judged not to be scientifically or medically compatible with this study. Any participant in >4 studies a year and/or has participated in a clinical trial within 1 month of expected dosing date. History or presence of medical illness including, but not limited to, any cardiovascular, hepatic, respiratory, hematological, endocrine, psychiatric, or neurological disease, convulsions, or any clinically significant laboratory abnormality that, in the judgment of the investigator, indicate a medical problem that would preclude study participation. *Other inclusion and exclusion criteria may apply*
Sites / Locations
- ICON plc. Van Swietenlaan 6Recruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
QRL-101
Placebo
Single-ascending doses of QRL-101 will be administered orally to healthy participants
Single-ascending doses of comparator placebo will be administered orally to healthy participants