Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP (MOST)
Hiv, Opioid Use Disorder
About this trial
This is an interventional prevention trial for Hiv focused on measuring people who inject drugs, HIV, cognitive dysfunction, pre-exposure prophylaxis, multiphase optimization strategy, medication for opioid use disorder, opioid use disorder
Eligibility Criteria
Inclusion Criteria: being 18 years or older meeting DSM-V criteria for opioid dependence and being newly prescribed and adherent to Medication for Opioid Use Disorder (e.g., methadone, buprenorphine) at the APT Foundation, Inc. showing mild cognitive impairment based on the Montreal Cognitive Assessment (MoCA) screening having initiated Pre-Exposure Prophylaxis (PrEP) within the past week confirming HIV-negative status through proof of PrEP prescription reporting unsafe injection drug use practices or unprotected sex within the past 3 months having a cell phone being able to read and understand in English Exclusion Criteria: unable to provide consent actively suicidal actively homicidal actively psychotic display MoCA scores suggestive of dementia
Sites / Locations
- APT FoundationRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
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Arm 12
Arm 13
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Arm 16
Active Comparator
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Condition 1
Condition 2
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Condition 16
Standard CHRP Intervention Components
Standard CHRP Intervention Components and Information Processing Components
Standard CHRP Intervention Components and Memory Components
Standard CHRP Intervention Components, Information Processing Components, and Memory Components
Standard CHRP Intervention Components, Executive Functioning Components
Standard CHRP Intervention Components, Information Processing Components, and Executive Functioning Components
Standard CHRP Intervention Components, Memory Components, and Executive Functioning Components
Standard CHRP Intervention Components, Information Processing Components, Memory Components, and Executive Functioning Components
Standard CHRP Intervention Components and Attention Components
Standard CHRP Intervention Components, Information Processing Components, and Attention Components
Standard CHRP Intervention Components, Memory Components, and Attention Components
Standard CHRP Intervention Components, Information Processing Components, Memory Components, and Attention Components
Standard CHRP Intervention Components, Executive Functioning Components, and Attention Components
Standard CHRP Intervention Components, Executive Functioning Components, Attention Components, and Information Processing Components
Standard CHRP Intervention Components, Executive Functioning Components, Attention Components, and Information Processing Components
Standard CHRP Intervention Components, Executive Functioning Components, Attention Components, Information Processing Components, and Memory Components