Multiparametric Imaging-based Intraoperative Navigation for Guidance of Surgical Resection and Postoperative Radiotherapy in Patients With Head-and-neck Tumors (NAVIGATORR)
Head and Neck Tumors
About this trial
This is an interventional treatment trial for Head and Neck Tumors
Eligibility Criteria
Inclusion Criteria: Diagnosis of a malignancy (squamous cell carcinoma (SCC), adenocarcinoma (AC), mucoepidermoid carcinoma (MEC), adenoidcystic carcinoma (ACC)) of the midface, upper jaw and skull-base (e.g. based on imaging-studies and/or biopsies) Indication of surgical tumor resection according to multidisciplinary tumor conference Probably indication for postoperative radiotherapy (e.g. T3/4 tumor) Medical operability and written informed consent of the patient to undergo surgical resection (as indicated clinically) Patient age ≥ 18 years Karnofsky performance index ≥ 60% For women with childbearing potential: adequate contraception Ability of subject to understand character and individual consequences of the trial Written informed consent to participate in this trial Exclusion Criteria: Contraindications against radiotherapy, especially pregnant or lactating women Refusal of the patient to take part in the study Participation in another competing clinical study or observation period of competing trials