Preoperative Boost Associated With Neoadjuvant Chemotherapy in Luminal B Breast Cancer
Breast Cancer, Radiotherapy
About this trial
This is an interventional treatment trial for Breast Cancer focused on measuring Luminal B Breast Cancer, Neoadjuvant radiation therapy, Neoadjuvant chemotherapy
Eligibility Criteria
Inclusion Criteria: Luminal B-like BC, cT1-2 Indication for neoadjuvant chemotherapy Exclusion Criteria: Pregnancy Breast feeding Patient not available for follow up
Sites / Locations
- IRCCS Azienda Ospedaliero-Universitaria di BolognaRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Interventional group
observational cohort
Patients will be treated on the primary tumour with a total dose of 24 Gy (8 Gy x 3 fractions QD) within 2 weeks from the start of neoadjuvant chemotherapy
This cohort will include patients fulfilling inclusion criteria who refuse enrollment in the interventional cohort and patients where SBRT boost appears not feasible after enrollment for technical issues