The Effect of Multiple Micronutrient Supplements in Reducing Anemia in Women of Reproductive Age
Anemia

About this trial
This is an interventional treatment trial for Anemia focused on measuring Multiple Micronutrient Supplements, Iron-folic acid, Anemia, Hemoglobin, Women of reproductive age
Eligibility Criteria
Inclusion Criteria: Age range of 18-49 years. Mildly anemic (Hb=11.0-11.9 g/dl) or moderately anemic (Hb=8.0-10.9 g/dl) woman Permanent residents (lived for at least six months in the enumeration area) Exclusion Criteria: A woman whose age is below or above the age range 18-49 year A pregnant woman Severely ill and incapacitated woman Non-permanent resident in the enumeration area Severely anemic (Hb <8.0 g/dl) woman A woman with Hb ≥12 g/dl
Sites / Locations
- Ethiopian Public Health Institute
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Placebo Comparator
Multiple micronutrient supplement arm
Iron-folic acid supplement arm
Control arm
The participants in this arm will receive United Nations International Multiple Micronutrient-Multiple Micronutrient Supplements. The recommended doses of UNIMMAP-MMS are vitamin A as retinol acetate (800 µg RAE), vitamin D as cholecalciferol (5 µg), vitamin E as alpha-tocopherol succinate (10 mg), vitamin C as ascorbic acid (70 mg), vitamin B1 as thiamin mononitrate (1.4 mg), vitamin B2 as riboflavin (1.4 mg), vitamin B3 as nicotinamide (18 mg), vitamin B6 as pyridoxine hydrochloride (1.9 mg), vitamin B12 as cyanocobalamin (2.6 µg), folic acid (680 µg), iron as ferrous fumarate (30 mg), zinc as zinc oxide (15 mg), copper as copper oxide (2 mg), selenium as sodium selenite (65 µg), iodine as potassium iodide (150 µg). The UNIMMAP-MMS in the tablet form will be used. We will give the supplementation twice a week and follow the study participants for 17 weeks.
The participants in this arm will receive Iron-Folic Acid (IFA) supplements. The recommended doses of iron-folic acid are 30-60 mg of elemental iron and 400 µg of folic acid combined. In this trial, we will use ferrous sulfate with 30 mg of iron and 400 µg of folic acid in the form of capsule. The supplementation will be given to the study subjects twice a week for 17 weeks.
The participants in this arm will receive placebos made of sugar (lactose anhydrous). There is no active ingredient in the placebos. The placebos are lactose powder filled in the capsule. We will give placebos twice a week and will follow the study subjects for 17 weeks. The study subjects in this arm will be compensated with UNIMMAP-MMS at the end of the intervention.