Evaluate the Effect of Nasal Spray in the Prevention of RTI in Children With Pre-school Wheezing
Wheezing, Recurrent Respiratory Tract Infections
About this trial
This is an interventional prevention trial for Wheezing focused on measuring RRI, Wheezing, Medical Device, Resveratrol
Eligibility Criteria
Inclusion Criteria: Children diagnosed with wheezing Patients aged between 3 and 6 years (inclusive) at the time of enrollment of both genders Signature of the informed consent Availability of a mobile phone capable of installing VIR@PP Exclusion Criteria: Inability to adequately understand the Italian language Presence of autoimmune pathologies, immunodeficiency, neuromuscular diseases, congenital cardiomyopathies, metabolic diseases Presence of other syndromes and genetic pathologies Patients on therapy with other drugs (steroids for topical and/or oral use) Abnormalities of the nose or other conditions (e.g. severe hypotonia etc…) which make the administration of a nasal spray impossible or unsafe Denial of informed consent Participation in other clinical studies
Sites / Locations
- University of Campania Luigi VanvitelliRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Resveratrol + CMG
Isotonic solution
Medical device: nasal spray based on resveratrol associated with carboxymethylbetaglucan in isotonic solution
Medical Device with isotonic solution