Invasive and Clinical Features in Patients With Brugada Syndrome Undergoing Catheter Ablation
Brugada Syndrome
About this trial
This is an interventional treatment trial for Brugada Syndrome focused on measuring Brugada syndrome, Radiofrequency catheter ablation, Electroanatomic mapping, Invasive electrophysiological study
Eligibility Criteria
Inclusion Criteria: Patients with a type 1 Brugada ECG pattern, as characterized by ST-segment elevation (≥2mm) with upward concavity associated with T-wave inversion, in at least one of the right precordial leads, positioned at the second, third or fourth intercostal space, either spontaneously or induced by a provocative test with Class I anti-arrhythmic drugs according to Vaughan Williams Patients clinically stable for at least six months before the enrollment Able to cope with follow-up visits up to one year after the intervention Patients who have signed the written informed consent Exclusion Criteria: Pregnant women Patients with structural heart disease Patients with a known cardiac or systemic autonomic disorder Patients with a history of previous right ventricular outflow tract ablation
Sites / Locations
- Instituto do Coração - InCor - HC/FMUSPRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Ablation
Control
Radiofrequency catheter ablation of the abnormal - prolonged and fragmented - electrophysiologic substrate of Brugada syndrome
Femoral venous punctions, catheter insertion, programmed electrical stimulation and electroanatomic mapping, with a similar duration to the ablation procedure