Intensive Postpartum Antihypertensive Treatment (IPAT)
Hypertensive Disorder of Pregnancy
About this trial
This is an interventional prevention trial for Hypertensive Disorder of Pregnancy
Eligibility Criteria
Inclusion Criteria: HDP diagnosis (gestational hypertension or preeclampsia) according to ACOG guidelines Postpartum day 0-3 and prior to discharge Able to communicate in English or in Spanish Age 18 - 45 Exclusion Criteria: Pre-gestational hypertension Pre-gestational diabetes ( type 1 or type 2) Intent to transfer postpartum to an outside institution of the participating centers Known allergy to nifedipine or other significant contraindication to nifedipine Inability or unwillingness to provide informed consent
Sites / Locations
- Froedtert HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Intervention arm
Active control arm
Intervention group - intensive postpartum BP control with Nifedipine initiation at SBP≥140 mmHg or DBP≥90 mmHg and maintaining BP at <140/90 mmHg during the first 6 weeks postpartum. In addition, participants will receive education on healthy lifestyle following AHA LE8.
Active control group - a group of usual care that follows ACOG recommendations2 with Nifedipine initiation at SBP≥160 mmHg or DBP≥110 mm Hg and maintaining BP at <160/110 mmHg during the first 6 weeks postpartum. In addition, participants will receive education on healthy lifestyle following AHA LE8.