Efficacy of Lauric Acid, a Dietary Fatty Acid, in Modifying the Latent Reservoir of HIV (FATHIV)
HIV Infections
About this trial
This is an interventional treatment trial for HIV Infections focused on measuring lauric acid, HIV, antiretroviral treatment
Eligibility Criteria
Inclusion Criteria: HIV-1 infected men or women ≥18 years old Not having interrupted current antiretroviral treatment at least 6 months before the screening visit. Acceptable stable ART regimens prior to screening include 2 more NRTIs: INI or NNRTI or boosted PI. Documented prior evidence of at least 2 years prior to enrollment with a serum HIV RNA load of <50 RNA copies/ml (viral load of >50 copies but <200 is allowed). Plasma HIV-1 RNA <50 c/ml at screening visit. CD4 T cell count > 300 cells/µL at screening visit. A woman may be eligible to enroll and participate in the study if: Not pregnant, not of childbearing potential or physically unable to become pregnant You are of childbearing potential with a negative pregnancy test at the screening visit and agree to use contraception to prevent pregnancy. Exclusion Criteria: Have suffered any significant acute illness in the last 8 weeks. Having been diagnosed in the past or present with an AIDS-defining illness Previous CD4 T cell count <200 cells/μL. Having suffered an infection with Hepatitis B or C Having any disease or condition that in the investigator's opinion is not appropriate for the patient's participation in the study.
Sites / Locations
- Hospital Universitario Vall d´HebronRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Placebo Comparator
Experimental
Experimental
Control group
Experimental group 1
Experimental group 2
Dietary supplementation
1.5 grams once daily during 48 weeks
3 grams once daily during 48 weeks