Effect of Epidural Analgesia on Burst Suppression
Post-operative Delirium, Cognitive Dysfunction, Electroencephalography
About this trial
This is an interventional prevention trial for Post-operative Delirium focused on measuring burst suppression, delirium, electroencephalography, anesthesia, regional anesthesia
Eligibility Criteria
Inclusion Criteria: American Society of Anesthesiologists (ASA) Physical Status 1-3 Hip or knee arthroplasty surgery Exclusion Criteria: severe renal failure (need for renal replacement therapy) severe liver failure (child-pudg grade c) body mass index >40 long-term use of some drugs (sedatives, tricyclic antidepressants, narcotic painkillers) having a disease related to the nervous system having a psychiatric disease having a history of substance abuse having consumed 2 or more glasses of alcohol per day in the last 1 year contraindications for neuraxial block allergy to drugs to be used emergency surgeries patient's refusal to accept the procedure hearing and visual impairment anesthesia awareness history preoperative delirium
Sites / Locations
- Bezmialem Vakif University HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Epidural analgesia
placebo
Eeg monitoring will be implemented with Sedline monitor(Masimo Irvine CA) 5 minutes before epidural catheter insertion, 30 minutes after epidural catheter insertion, during surgery and 5 minutes after extubation.
Eeg monitoring will be implemented with Sedline monitor (Masimo Irvine CA) 5 minutes before epidural catheter insertion, 30 minutes after epidural catheter insertion, during surgery and 5 minutes after extubation.