Evaluation of Efficacy and Safety of Profhilo® Structura for the Correction of Acne Scars of the Face

Inclusion Criteria: caucasian subjects of both sexes; age >18years asking for acne scars treatment; presenting acne scars (ice picks, rollings, boxcars); available and able to return to the study site for the post-procedural follow-up examinations; agreeing to present at each study visit without make-up; accepting to not change their habits regarding food, physical activity, make-up use, face cosmetic and cleansing products; accepting not to expose their face to strong UV irradiation (UV session, or sun bathes) during the entire duration of the study, without appropriate sun protection; accepting to sign the Informed consent form. Exclusion Criteria: Dependent on the volunteers' characteristics: smokers; performing in the 6 month before the trial beginning HA injections, radiofrequency treatment, toxin treatment; contraindication or know allergy to the devices' components or to the treatment; participation in a similar study actually or during the previous 3 months known pregnancy occurrence of pregnancy during the study Dependent on a clinical condition: Dermatological disease: Dermatitis; presence of cutaneous disease on the tested area,different from those under study recurrent facial/labial herpes; clinical and significant skin condition on the test area (e.g. active eczema, psoriasis, severe rosacea, scleroderma, local infections and severe acne). Dependent on a clinical condition: General disease: Diabetes, coagulation disorders, connective tissue disorders, lipodystrophy or other systemic disease; HIV and/or immunosuppressive disease; cancerous or precancerous lesions in the either right or left midface; severe allergies manifested by a history of anaphylaxis, or history or presence of severe multiple allergies; alcohol or drug abusers; Dependent on a pharmacological treatment: Anti-inflammatory drugs, anti-histaminic, topic and systemic corticosteroids, narcotic, antidepressant, immunosuppressive drugs (with except of contraceptive or hormonal treatment starting more than 1 year ago); assumption of drugs able to influence the test results in the investigator opinion. The use of other drugs, not mentioned above, can be authorized by the Investigator. The trade name, the dosage, the start and stop date of the therapy will be reported on Case Record Form (CRF).