Dexamethasone vs Ondansetron After Cesarean Delivery
Nausea and Vomiting, Postoperative, Cesarean Section Complications, Spinal Epidrual
About this trial
This is an interventional prevention trial for Nausea and Vomiting, Postoperative
Eligibility Criteria
Inclusion Criteria: Healthy women (ASA 2) Between 18 and 45 years old Singleton term pregnancies Scheduled or non-labor cesarean delivery Neuraxial (spinal or combined-spinal epidural) anesthesia Exclusion Criteria: Refusal to participate Known allergy or contraindication to any medication used in the study Significant medical or obstetrical disease (ASA ≥ 3) Antiemetic use within 24 hours preceding cesarean delivery Insulin dependent diabetes Hyperemesis gravidarum or chronic antiemetic use History of daily or near-daily steroid use during pregnancy Opioid use disorder or other chronic pain syndrome Opioid use during pregnancy Use of antipruritus medication, pruritic urticarial papules of pregnancy, or cholestasis of pregnancy
Sites / Locations
- Beth Israel Deaconess Medical Center
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Ondansetron
Dexamethasone
ondansetron 4 mg intravenous, given once after initiation of anesthesia
dexamethasone 8 mg intravenous, given once after initiation of anesthesia