Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting
Urinary Tract Infections
About this trial
This is an interventional treatment trial for Urinary Tract Infections focused on measuring gentamicin, single dose antibiotic treatment
Eligibility Criteria
Inclusion Criteria: At least 18 years of age, woman, pre-menopausal, non-pregnant with clinical signs of urinary tract infection and nitrite positive urine. Exclusion Criteria: Contraindications include hypersensitivity to gentamicin or other aminoglycosides. Patients younger than 18 years of age. Pregnant or post-menopausal patients. Patients without symptoms of UTI, nitrite negative urine, or any patient with working diagnosis of complicated UTI such as pyelonephritis or any patient catheterized. ANY history of pre-existing renal impairment. Patient that has any listed or reports taking ANY nephrotoxic or wit drug-drug interaction medication in the past 7 days (see Appendix 5). ANY history of hearing loss, tinnitus, or vertigo. ANY patient that has received general anesthesia or neuromuscular blockade in past 7 days. Patients with ANY history of neuromuscular disorders including: myasthenia gravis, amyotrophic lateral sclerosis, muscular dystrophy, botulism, congenital myasthenic syndromes, congenital myopathies, myositis, Lambert-Eaton syndrome, mitochondrial myopathy, myotonic dystrophy, neuromyotonia, or peripheral neuropathy. Patients with ANY history of thrombocytopenia. Patient that has any listed or reports taking ANY anticoagulants in the past 7 days.
Sites / Locations
- St. Elizabeth Youngstown HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Gentamicin
Standard of Care
Subjects will be given one (1) injection intramuscular gentamicin 5 mg/kg (actual body weight unless patient is >120% ideal body weight in which case adjusted body weight will be utilized).
Oral antibiotic prescription