Artificial Tears, Tear Lipids and Tear Film Dynamics (AlconAT)
Dry Eye
About this trial
This is an interventional treatment trial for Dry Eye focused on measuring Dry Eye, Tear Film Lipid Layer Dynamics, Tear Film Stability
Eligibility Criteria
Inclusion Criteria: Best Corrected Visual Acuity of 20/30 or better; Experiencing Dry Eye symptoms (baseline OSDI score >= 13); Exclusion Criteria: Currently experiencing active ocular inflammation or infection; Currently using topical eye medication (not including over-the-counter eyedrops); Having systemic health conditions or using prescription medications (including but not limited to isotretinoin derivatives) that could alter tear film physiology; Having a history of severe ocular trauma, ocular surgery, or diabetes; Being pregnant or breast feeding; Being a current contact lens wearer; Currently having a condition or being in a situation which, in the examiner's opinion, may put the subject at significant risk, may confound the study results, or may otherwise significantly interfere with their participation in the study;
Sites / Locations
- Clinical Research Center, School of Optometry, University of California, BerkeleyRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Placebo Comparator
Active Comparator
Active Comparator
Systane Complete PF (Treatment)
Refresh Relieva PF (Control)
Refresh Optive Mega-3 PF (Active Comparator 1)
CVS Health Lubricant Eye Drop (PG 0.6%) (Active Comparator 2)
Masked subjects assigned to Arm 1 will use Systane Complete PF artificial tear drops 4 times per day (QID) to treat dry eye symptoms over a 3 month period.
Masked subjects assigned to Arm 2 will use Refresh Relieva PF artificial tear drops 4 times per day (QID) to treat dry eye symptoms over a 3 month period.
Masked subjects assigned to Arm 3 will use Refresh Optive Mega-3 PF artificial tear drops 4 times per day (QID) to treat dry eye symptoms over a 3 month period.
Masked subjects assigned to Arm 4 will use CVS Health Lubricant Eye Drop (PG 0.6%) artificial tear drops 4 times per day (QID) to treat dry eye symptoms over a 3 month period.