Impact of Intravenous Iron on Musculoskeletal Function in Older Adults (FERIDA)
Iron Deficiency Anemia
About this trial
This is an interventional basic science trial for Iron Deficiency Anemia focused on measuring Iron Deficiency Anaemia, Skeletal Muscle Function, Musculoskeletal, Ageing
Eligibility Criteria
Inclusion Criteria: Anaemia attributable to iron deficiency Haemoglobin < 120 g/L in women, Hb < 130 g/L in men Ferritin ≤100 ng/mL or ≤300 ng/mL if transferrin saturation (TSAT) ≤30% Age ≥ 60 to 85 years Ambulatory individuals Written informed consent Exclusion Criteria: Patients already taking intravenous or oral iron BMI > 40 kg/m² Uncontrolled hypertension/ diabetes Potential medication interactions Hemochromatosis or iron storage disorders Recent treatment with IV antibiotics or red blood cell transfusion Dialysis dependent History of malignancy Pregnant or lactating women Severe hepatic and renal dysfunction Advanced cardiovascular disease and COPD Advanced Neuromuscular disorder Obvious cognitive disability and psychological illness Current treatment with systemic steroids or any other substantive medication Alcohol or any other drug abuse
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Intravenous iron therapy group
Active Control Group
This group will receive intravenous iron calculated based on body weight and level of anaemia (hemoglobin concentration), as per the iron therapy's SPC.
This group will receive oral ferrous sulphate prescribed by their GP Randmisation: Simple randomisation/parallel assignment/single-blinded