External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing
Dysphagia
About this trial
This is an interventional treatment trial for Dysphagia
Eligibility Criteria
Inclusion Criteria: Healthy volunteers must be at least 18 years of age or older. Exclusion Criteria: Subjects with cervical spine disorders. Subjects with neurological disorders like dementia, cerebrovascular diseases other than Parkinson's Disease Subjects with carotid artery bruit or carotid vascular disorders. Subjects suffering from muscle diseases like muscular dystrophies, myopathies. Subjects with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders. Subjects with any current esophageal symptoms like heartburn, dysphagia, chest pain or regurgitation. Subjects cannot have previous head or neck surgery or radiation. Subjects unable to tolerate nasal intubation. Subjects with significant bleeding disorders for whom nasal intubation has been deemed contraindicated. Subjects with a known upper airway or esophageal obstruction preventing the passage of the manometry probe. Subjects with autonomic dysfunction. Subjects having a history of allergy to lidocaine and barium. Subjects who are pregnant or lactating. Subjects who have advanced medical disorders (e.g.: chronic obstructive pulmonary disease (COPD), congestive heart failure, cirrhosis, cancer, chronic renal failure, etc.). Subjects who are medically unstable.
Sites / Locations
- Medical College of WisconsinRecruiting
Arms of the Study
Arm 1
Experimental
Pharyngeal exerciser group
Test that application of the pharyngeal exerciser increases the workload of muscles involved in pharyngeal phase of swallowing as evidenced manometrically by changes in Pharyngeal peak pressures Pharyngeal (velopharynx, oropharynx and hypopharynx) contractile duration Pharyngeal (velopharynx, oropharynx and hypopharynx) contractile integral Hypopharyngeal intrabolus pressure and duration UES nadir pressure UES relaxation time Baseline UES pressure