Assessment of Recovery After Adductor Canal Block Analgesia in Unilateral Prosthetic Knee Surgery (IPACKNEE)

Inclusion Criteria: Patient with a score "American Society of Anesthesiologists" I to III; Patient undergoing initial unilateral prosthetic knee replacement surgery for osteoarthritis; Patient eligible for analgesia by block of the adductor canal associated with additional infiltration; Patient accepting to follow the enhanced recovery program after surgery; Patient who signed an informed consent form to participate in the study. Exclusion Criteria: Patient with a known allergy to a study product; Patient having undergone previous surgery with a prosthesis on the knee to be operated on; Patient with morbid obesity (Body Mass Index > 40); Patient with a pre-existing inability to walk; Patient with a history of chronic neuropathic pain in the leg undergoing surgery; Patient with heart failure with impaired ejection fraction; Patient with a history of drug addiction; Patient chronically taking level III analgesics; Patient taking gabapentin or pregabalin chronically; Patient with severe renal or hepatic impairment; Patient with a high level of dependence, defined by level 1 or 2 of the Iso-Ressources Group; Protected patient (under legal protection, or deprived of liberty by judicial or administrative decision); Patient unable to understand the information related to the study (linguistic, psychological, cognitive reasons, etc.); Pregnant or likely to be pregnant (of childbearing age without effective contraception) or breastfeeding; Patient participating in another clinical trial, or in a period of exclusion from another clinical trial; Patient not benefiting from a social security scheme.