Effect of Nutritional Management on RIOM in Patients With Advanced Head and Neck Cancer
Head and Neck Cancer, Nutrition Related Cancer, Radiation-Induced Mucositis
About this trial
This is an interventional supportive care trial for Head and Neck Cancer focused on measuring Head and Neck Cancer, Malnutrition, Radiation-induced Oral Mucositis, nutrition management
Eligibility Criteria
Inclusion Criteria: Aged between 18 and 80 years old Advanced head and neck cancer (III-IV inoperable) is clearly diagnosed Predicted survival time > 3 months Radical radiotherapy combined with chemotherapy or immunotherapy was performed in our hospital The patient has clear consciousness and no communication disorder Informed consent and voluntary participation in this study Exclusion Criteria: Patients with previous surgery or radiotherapy for head and neck cancer Patients with concurrent or previous history of other tumors Distant metastasis Patients with allergy, intolerance or contraindication to enteral nutrition or parenteral nutrition Severe renal insufficiency (eGFR<30ml/min/1.73m2) Combined with poorly controlled metabolic diseases such as diabetes Doctors or researchers deem that they are not suitable to participate in the study.
Sites / Locations
Arms of the Study
Arm 1
Other
Peri-radiotherapy nutrition management group
Nutritional management was performed by clinical pharmacists and registered dietitians to develop nutritional intervention strategies based on patient clinical assessment and nutritional assessment. PG-SGA score was 0-3 points, and diet guidance was given. PG-SGA score > 4 points, artificial nutrition intervention was carried out, and the way and amount of nutritional intervention were clarified to achieve the final daily energy and protein target requirements. Nutritional interventions and assessments were adjusted over time.