The level of diagnostic confidence based on routine histology only
The level of diagnostic confidence for a given diagnosis is established according to a quantitative scale ranging from '0' (absolute rule-out) to '10' (diagnostic certainty). A visual guide for scale use is provided with scores <1 corresponding to "alternate diagnosis", scores >=1 and <4 corresponding to "indeterminate", scores >=4 and <7 corresponding to "probable", and scores >=7 corresponding to "highly probable" categories.
The level of diagnostic confidence achieved at multidisciplinary assessment (MDA)-2
The level of diagnostic confidence for a given diagnosis is established according to a quantitative scale ranging from '0' (absolute rule-out) to '10' (diagnostic certainty). A visual guide for scale use is provided with scores <1 corresponding to "alternate diagnosis", scores >=1 and <4 corresponding to "indeterminate", scores >=4 and <7 corresponding to "probable", and scores >=7 corresponding to "highly probable" categories.
Change in the level of diagnostic confidence for the most favoured diagnosis between multidisciplinary assessment (MDA)-1 and multidisciplinary assessment (MDA)-2
The level of diagnostic confidence for a given diagnosis is established according to a quantitative scale ranging from '0' (absolute rule-out) to '10' (diagnostic certainty). A visual guide for scale use is provided with scores <1 corresponding to "alternate diagnosis", scores >=1 and <4 corresponding to "indeterminate", scores >=4 and <7 corresponding to "probable", and scores >=7 corresponding to "highly probable" categories.
Classification according to ATS/ERS at MDA-1
Classification according to the American Thoracic Society / European Respiratory society: Alternative diagnosis / Indeterminate / Probable / Highly probable
Classification according to ATS/ERS at MDA-2
Classification according to the American Thoracic Society / European Respiratory society: Alternative diagnosis / Indeterminate / Probable / Highly probable
Inter-histologist concordance for ATS/ERS categories
Inter-histologist concordance for ATS/ERS categories
Longest length (mm) of biopsy specimens
Longest length (mm) of biopsy specimens
Volume (cc) of biopsy specimens
Volume (cc) of biopsy specimens
Weight (g) of biopsy specimens
Weight (g) of biopsy specimens
Numerical scale for biopsy quality
The histologist ranks biopsy quality from worst imaginable (0) to excellent (10).
Preparation time (minutes)
Minutes lapsed between entering the surgical ward and entering the operating room (OR)
OR time (minutes)
Minutes lapsed between entering and exiting the OR
Recovery room (RR) time (minutes)
Minutes lapsed between exiting the OR and exiting the surgical ward.
Post-RR time (hours)
Hours lapsed between exit from surgical ward, and discharge from hospital
First drink time (minutes)
Minutes lapsed between application of last bandage on surgical wounds to first drink
Post-operative fasting time (hours)
Hours lapsed between application of last bandage on surgical wounds to first meal
Time with chest tube in place (hours)
Hours lapsed between application of last bandage on surgical wounds to removal of chest tube
Visual analogue scale score for post-operative pain
The patient will be asked to evaluate his/her level of post-operative pain using a numeric rating scale (0-10) the morning after surgery where 0 represents no pain, and 10 represents the worse possible pain.
Patient satisfaction (satisfied vs unsatisfied)
The patient will be asked to evaluate his/her satisfaction (satisfied vs unsatisfied)
Time to dischargeability
Dischargeability is defined as meeting the following criteria: (i) satisfactory pain control via oral analgesia; (ii) ability to mobilize and return to usual autonomy; (iii) absence of clinical, laboratory and radiological complications; (iv) stable respiratory state compatible pre-surgical state and home discharge; (v) vital signs are normal for the patient; (vi) chest tube removal >12 hours.
Length of initial hospitalization stay (hours)
Length of initial hospitalization stay (hours)
Cumulative days of hospitalization
Cumulative days of hospitalization
Cumulative days of exacerbation
Cumulative days of exacerbation
Days alive, not exacerbating and not in hospital
Days alive, not exacerbating and not in hospital
Forced vital capacity (litres)
Forced vital capacity (litres)
Forced vital capacity (litres)
Forced vital capacity (litres)
Forced vital capacity (% theoretical value)
Forced vital capacity (% theoretical value)
Forced vital capacity (% theoretical value)
Forced vital capacity (% theoretical value)
Euroqol 5 dimensions 5 levels questionnaire: mobility dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: mobility dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: self-care dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: self-care dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: usual activities dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: usual activities dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: pain/discomfort dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: pain/discomfort dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: anxiety/depression dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Euroqol 5 dimensions 5 levels questionnaire: anxiety/depression dimension score
In its original version, this self-administered questionnaire consists of two pages: the first contains the EQ-5D descriptive system and the second a visual analogue scale. The descriptive system has five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), each described by five levels of intensity ("no problems", "slight problems", "moderate problems", "severe problems" and "extreme problems or complete inability"). The respondent must indicate one intensity level for each dimension.
Presence / absence of complications
Complications will be listed and classified (Minor: (1) Any complication without need for pharmacologic treatment or other intervention; (2) Any complication that requires pharmacologic treatment or minor intervention only; Major: (3) Any complication that requires surgical, radiologic, endoscopic intervention, or multitherapy; (3a) Intervention does not require general anesthesia; (3b) Intervention requires general anesthesia; (4) Any complication requiring intensive care unit management and life support; (4a) Single organ dysfunction; (4b) Multiorgan dysfunction; (5) Any complication leading to the death of the patient.