Autophagy Dysfunction in Hidradenitis Suppurativa (AUTOPH-HS)
Hidradenitis Suppurativa (HS)
About this trial
This is an interventional diagnostic trial for Hidradenitis Suppurativa (HS)
Eligibility Criteria
Inclusion Criteria: Subject aged 18 to 65 years (included) Subject diagnosed with HS for at least 1 year Subject diagnosed with moderate-to-severe HS defined by HS PGA≥3 Subject presenting an HS with inflammatory phenotype defined by the presence of folliculitis, nodules and/or abcesses Subject suffering from at least 4 flares/year and presenting 5 active inflammatory lesions (nodules and/or abcesses) Subject able to read, understand and give documented informed consent Subject willing and able to comply with the protocol requirements for the duration of the study Subject with health insurance coverage according to local regulations Exclusion Criteria: - Pregnancy or breast-feeding women Subject currently experiencing or having a history of other concomitant skin or systemic inflammatory conditions that could constitute a bias (i.e. psoriasis, Crohn's Disease, etc.) Subject with any additional condition that, in the opinion of the investigator, may interfere with the assessment or put the subject at risk Linguistic or mentally incapacity to sign the consent form Subject protect by the law (adult under guardianship, or hospitalized in a public or private institution for a reason other than study, or incarcerated) Subject in an exclusion period from a previous study or who is participating in another clinical trial using a drug
Sites / Locations
Arms of the Study
Arm 1
Experimental
HS Patients
50 adult subjects suffering from moderate to severe HS, aged 18 to 65, diagnosed for at least 1 year