Fluid Challenge and Plasma Volume, During Surgery (FC-VE)
Colorectal Cancer, Urologic Cancer, Gynecologic Cancer
About this trial
This is an interventional treatment trial for Colorectal Cancer focused on measuring laparoscopic surgery, fluid therapy, plasma volume
Eligibility Criteria
Inclusion Criteria: Written consent to participate in the study For women: relevant contraceptive, menopausal or a negative pregnancy test. ASA category I to III Laparoscopic abdominal surgery, with a duration of at least 90 minutes. 18 to 80 years Exclusion Criteria: Patients with known cardiac failure <18 or >80 years known allergy to albumin extracellular hyperhydration or hypervolemia kidney failure pregnancy or planned pregnancy
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Experimental
acetated Ringers
albumin 5%
albumin 20%
The circulatory effect of a bolus infusion with 4 ml/kg body weight of acetated Ringers will be studied. If cardiac output increase with 10% a second bolus will be infused and further studied.
The circulatory effect of a bolus infusion with 4 ml/kg body weight of Albumin 5% will be studied. If cardiac output increases with 10% a second bolus will be infused and further studied.
The circulatory effect of a bolus infusion with 1 ml/kg body weight of Albumin 20% will be studied. If cardiac output increase with 10% a second bolus will be infused and further studied.