Effects of the Contraceptive Implant in Women With Sickle Cell Disease (SCD CURE)
Sickle Cell Disease
About this trial
This is an interventional treatment trial for Sickle Cell Disease
Eligibility Criteria
Inclusion Criteria: Female aged 18-45 Diagnosis of sickle cell disease (SS or SB0) Report of at least 1 vaso-occlusive pain episode per month on average in the previous 6 months Willing to discontinue any hormonal contraception at the time of enrollment. Washout period of 1 month required for all hormonal contraception prior to enrollment in the study. Access to a device with text messaging capability Must be able to read and understand English Willing to comply with study procedures Exclusion Criteria: SC Disease Use of Depo Provera in the past 6 months Changes to sickle cell medications in the past 3 months Contraindications to use of Nexplanon device as per clinical standards Currently pregnant or pregnant within the last month or seeking to become pregnant Currently breastfeeding
Sites / Locations
- Penn Medicine University CityRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
Nexplanon
Baseline