Platelet Rich Plasma as an Adjunct Therapy at the Time of Transvaginal Native Tissue Prolapse Surgery (PRP)
Pelvic Organ Prolapse
About this trial
This is an interventional treatment trial for Pelvic Organ Prolapse
Eligibility Criteria
Inclusion Criteria: Desire surgical treatment via a transvaginal native tissue approach. Completed child-bearing Exclusion Criteria: Unable to follow-up, not willing to, or unable to participate in the proposed study Prior pelvic surgery within the past 12 months Prior anterior/apical suspension procedures Prior graft augmented prolapse surgery Pelvic/abdominal radiation Pelvic mass History of solid organ malignancy
Sites / Locations
- University of Alabama at BirminghamRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Adjunct Platelet rich plasma (PRP) therapy
Normal saline
Study Interventions: PRP will be injected in a systematic grid like fashion into the fibromuscular connective tissue of the anterior compartment following vaginal incision and dissection.
Placebo: Normal saline will be injected in a systematic grid like fashion into the fibromuscular connective tissue of the anterior compartment following vaginal incision and dissection.