Impact of Early Sepsis Care Guided by the National Early Warning Score 2 in the Emergency Department (NEWS-1-TRIPS)
Sepsis, Septic Shock
About this trial
This is an interventional treatment trial for Sepsis focused on measuring Sepsis, National Early Warning Score, Surviving Sepsis Campaign Hour-1 Bundle, Emergency Department, Implementation Sciences
Eligibility Criteria
Inclusion Criteria: ED patients aged ≥ 18 years who fulfil ALL of the following criteria: a clinical diagnosis of infection made by the treating emergency physicians require hospital admission a NEWS2 ≥ 5 Exclusion Criteria: age < 18 years currently pregnant neutropenic or post-chemotherapy fever, for which ED protocols for early antibiotics apply an advanced directive with a ceiling-of-care refusal of consent/pre-existing mental illness rendering consent impossible refusal of hospitalization
Sites / Locations
- Accident and Emergency Department, Pamela Youde Nethersole Eastern HospitalRecruiting
- Accident and Emergency Department, Prince of Wales HospitalRecruiting
- Accident and Emergency Department, Queen Mary HospitalRecruiting
- Accident and Emergency Department, Tuen Mun HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
NEWS-1 care
Standard care
During the interventional period, the 2018 Sepsis Hour-1 Bundle will be initiated in the ED if NEWS2 score ≥ 5.
During the standard care period, emergency physicians will assess the patients based on history, physical examination, laboratory tests, chest radiography or other imaging studies, and will offer treatment based on clinical expertise, intuition, and local or international guidelines