Concurrent Chemoradiotherapy Combined With Adjuvant Chemotherapy Treated Advanced Cervical Cancer

Inclusion Criteria: Cervical cancer confirmed by histopathology incloud squamous cell carcinoma, adenocarcinoma and adenosquamous carcinoma FIGO stage IB3, IIA2, IIB-IVA patients in 2018 Locally advanced cervical cancer patients received standard concurrent intensity-modulated chemoradiotherapy followed by three-dimensional afterloading treatment after diagnosis, and the effect reached CR after treatment Aged 18-75 years PS score 0-1 Serum hemoglobin >=100*10^9/L, blood platelet >= 100000/μL, absolute count of neutrophils>=1500/μL; 7.Serum creatinine <=1.5 UNL or creatinine clearance >= 60 ml/min; 8.Serum bilirubin <=1.5 UNL, AST (SGOT) and ALT (SGPT)<= 1.5 UNL Sign a formal informed consent to show that they understand that the study is in line with hospital and national policies .Estimated total survival > 6 months. Exclusion Criteria: Locally advanced cervical cancer patients received standard concurrent intensity-modulated chemoradiotherapy followed by three-dimensional afterloading treatment after diagnosis, and the effect unreached CR after treatment Patients who have received neoadjuvant chemotherapy and surgery Patients with cognitive impairment Patients with any distant metastases Patients with any other malignancy within 5 years Any other disease or condition is contraindications to chemoradiotherapy (e.g., active infection, 6 months after myocardial infarction, symptomatic heart disease, including unstable angina, congestive heart failure or uncontrolled arrhythmias, immunosuppressive therapy, etc.); 5.Pregnant or lactating women, or fertile women who do not use contraception Severe bone marrow dysfunction Patients with bleeding tendency Drug abusers or alcohol addicts Those who are known to have a third or fourth degree allergic reaction to any treatment in the study