Assessing a Natural Product Plus Bioadhesive Nanoparticle (BNP) Sunscreen
Skin Cancer
About this trial
This is an interventional prevention trial for Skin Cancer
Eligibility Criteria
Inclusion Criteria: Provision of signed and dated informed consent form Stated willingness to comply with all study procedures and availability for the duration of the study Women of child-bearing potential must have negative urine pregnancy test In good general health as evidenced by medical history Fair skinned with Fitzpatrick Scale skin types I, II or III using the following Skin Type and Sunburn and Tanning History (based on the first 30-45 minutes of sun exposure after a winter season of no sun exposure): I always burns easily; never tans (sensitive) II always burns easily; tans minimally (sensitive) III burns moderately; tans gradually (light brown) (normal) Exclusion Criteria: Individuals with active or a history of dermatological disorders-psoriasis, rosacea, eczema, vitiligo, lupus, dermatomyositis, etc Individuals known to be subject to any abnormal responses to sunlight, such as phototoxic or photoallergic response. Current use of medication (topical or systemic) that is known to produce abnormal sunlight responses. History of skin cancer (such as basal cell carcinoma, squamous cell carcinoma, melanoma) Family history of melanoma Presence of sunburn, suntan, scars, active dermal lesions or uneven skin tone on the test site. Skin type falling under the Fitzpatrick Scale skin types IV, V or VI using the following Skin Type and Sunburn and Tanning History (based on the first 30-45 minutes of sun exposure after a winter season of no sun exposure): IV Burns minimally; always tans well (moderate brown) (normal) V Rarely burns; tans profusely (dark brown) (insensitive) Use of sunscreen within the last week on the test site area (such that UV filter penetration may confound results) Febrile illness within 48 hours. Women with a positive urine pregnancy test
Sites / Locations
- Yale School of MedicineRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Other
Sunscreen
No treatment control
Portion of skin covered by sunscreen.
Portion of skin not covered by sunscreen.