Oral Immunotherapy in Young Children With Food Allergy (ORKA-NL)
Food Allergy
About this trial
This is an interventional treatment trial for Food Allergy focused on measuring Oral immunotherapy, infants, food allergy
Eligibility Criteria
Inclusion Criteria: An IgE-mediated food allergy to peanut, cashew, hazelnut, walnut, cow's milk and/or hen's egg as proven by sensitization to the specific allergen (sIgE > 0.35kU/l) and a positive oral food challenge. The fore-mentioned allergens are introduced into the diet of the child (the child is tolerant for the specific allergen(s)), or the child is diagnosed with a food allergy for the specific allergen(s). Exclusion Criteria: (Suspected) eosinophilic oesophagitis Uncontrolled asthma/ viral wheeze. The inability of parents to follow instructions, recognize allergic reactions or administer emergency medication. Participation in any other intervention study at the time of the OIT study, with the exception of studies on guided early introduction of highly allergenic foods.
Sites / Locations
- Deventer hospital
- Amsterdam UMC, location AMC
- Reinier de Graaf Gasthuis
- Martini hospital
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
oral immunotherapy
routine care
oral immunotherapy, maintenance phase with daily 300 mg allergenic protein during 1 year
strictly avoidance of the specific allergenic food