HU007 in Patients With Dry Eye Syndrome
Dry Eye Disease
About this trial
This is an interventional treatment trial for Dry Eye Disease
Eligibility Criteria
Inclusion Criteria Age over 19 Corneal staining score(Oxford grading) ≥ 2 and Schirmer test ≤ 10mm/5min (If Schirmer test = 0mm/5min, Nasal stimulation schirmer test ≥ 3mm/5min) and TBUT test ≤10 in at least one of both eyes Volunteer who have had more than one symptom of dry eye disease for at least 3 month before screening visit. Exclusion Criteria: The patients with clinically significant ocular disorders affected the test result Current or recent patients used dry eye syndrome medications (topical or systemic) that may affect the status SBP ≥140mmHg or DBP ≥ 90mmHg or HbA1c>9% Wearing contact lenses within 72 hr of screening visit Pregnancy or Breastfeeding
Sites / Locations
- Gyeongsang National University HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Active Comparator
HU007
Restasis
Moisview
Cyclosporine 0.02%, trehalose 3% 1 drop b.i.d at 12hr interval for 12 weeks
Cyclosporine 0.05% 1 drop b.i.d at 12hr interval for 12 weeks
trehalose 3% 1 drop b.i.d at 12hr interval for 12 weeks