Italian Cardioneuroablation Study for Neurocardiogenic Syncope Patients (ItalianCNA)
Neurally Mediated Syncope
About this trial
This is an interventional treatment trial for Neurally Mediated Syncope
Eligibility Criteria
Inclusion Criteria: Age between 18 and 60 years Patients with a clinical diagnosis of neuromediated syncope according to class I criteria of the ESC guidelines, Table 1 Clinical history of recurrent syncope (≥2 in the last year or ≥3 in the last 2 years), severe, not tolerated by the patient Documentation of ≥2 asystolic pauses >3 sec daytime on ECG monitoring by implantable loop recorder (ILR), with or without syncope Refusal by patient to perform pacemaker implantation Tilt test is recommended but not mandatory. Patients with negative tilt test are also enrollable. It can be either positive or negative. Exclusion Criteria: Absence of sinus dysfunction and atrioventricular node disease. Absence of structural heart disease Possible alternative diagnoses of syncope
Sites / Locations
- Policlinico CasilinoRecruiting
- Policlinico CasilinoRecruiting
Arms of the Study
Arm 1
Experimental
patients affected by Cardioinhibitory Neurocardiogenic Syncope