Effect of PEA on Muscle Recovery Following Resistance Exercise
Muscle Recovery, Muscle Soreness
About this trial
This is an interventional basic science trial for Muscle Recovery focused on measuring PEA, Skeletal muscle
Eligibility Criteria
Inclusion Criteria: Males between 18 and 35 years old Non-elite athletes (training load > 5h/wk) Good health status confirmed by a medical screening Body Mass Index (BMI) between 18 and 25 kg/m2 Masters the Dutch language Exclusion Criteria: Participant has a history of smoking Concomitant participation in another interventional Trial (e.g. with an investigational medicinal product, medical device or experimental surgical technique) Involvement in a structural resistance training program 6 months prior to the start of the experimental trial Any kind of injury/incapability that is a contra-indication to perform high-intensity resistance exercise Intake of any performance enhancing medication or nutritional supplement 6 months prior to the start of the experimental trial Use of PEA supplements or CBD related products (including CBD oil, cannabis or other substances containing cannabinoids) 1 year prior to the start of the experimental trial Blood donation within 3 months prior to the start of the experimental trial
Sites / Locations
- Exercise Physiology Research GroupRecruiting
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Experimental
Placebo
Palmitoylethanolamide (PEA) supplementation
Participants receive placebo supplements on two separate occasions in a randomized order. The placebo supplements contain 350 mg of maltodextrine. Placebo supplements are packaged in non-see-through hard capsules to assure that there are no differences in appearance or taste. Participants are instructed to ingest their supplement twice a day (in the morning and one hour before bedtime) for 6 consecutive days starting after collection of baseline measures.
Participants receive PEA supplements on two separate occasions in a randomized order. The PEA supplements contain 350 mg of Levagen+ (315 mg of PEA and 35 mg of excipients). Levagen+ consists for 90% of palmitoylethanolamide and for 10% of a mixture of coconut oil (fractionated), polyglycerol polyricinoleate, citrus oil, olive oil, lecithin, dl-alpha tocopheryl acetate, and silicon dioxide to improve the bioavailability of PEA. Both PEA supplements are packaged in non-see-through hard capsules to assure that there are no differences in appearance or taste. Participants are instructed to ingest their supplement twice a day (in the morning and one hour before bedtime) for 6 consecutive days starting after collection of baseline measures.