Nebulized Dexmedetomidine VS ODF Melatonin for Peri Operative Anxiety and Emergence Agitation in Pediatric Day Surgery
Anxiety Acute, Emergence Agitation
About this trial
This is an interventional prevention trial for Anxiety Acute
Eligibility Criteria
Inclusion Criteria: Patients of American Society of Anesthesiologists (ASA) physical status I & II both genders, ≥ 2 to 10 years, scheduled for elective day case surgery under general anesthesia Exclusion Criteria: parents' refusal for participation in the study ASA III and VI patients with history of chronic illness runny nose or upper respiratory tract infection Emergency surgeries with hemodynamic instability history of allergic reaction to dexmedetomidine or melatonin History of prematurity developmental delay central nervous system disorder, mental retardation, neurological or psychiatric illness that may be associated with anxiety and agitation (cerebral palsy, seizure, separation anxiety disorder, ADHD etc.). treatment with anticonvulsants and sedatives
Sites / Locations
- Ain shams university hospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Placebo Comparator
group D
group M
group C
will receive placebo ODF and nebulized dexmedetomidine (Precedex™ rxlist)
will receive placebo nebulizer and ODF melatonin (metacyst ™ nerhadou)
will receive placebo ODF and placebo 0.9% normal saline nebulizer