Botulinum Toxin Type a Iontophoresis for Postburn Hypertrophic Scar
Hypertrophic Scar
About this trial
This is an interventional treatment trial for Hypertrophic Scar focused on measuring Hypertrophic scar
Eligibility Criteria
Inclusion Criteria: Patient with hypertrophic scar (3-6) months after burn healing. Age range between 20-40 years. Male and female patients will participate in the study. All patients have a postburn hypertrophic scar at different body sites. All patients enrolled on the study will have their informed consent. Exclusion Criteria: Patients with prior medical histories of cardiac arrhythmias. Patients with cardiac pacemakers. Patients with orthopedic implants. Areas of skin with lesions and impaired sensation. During pregnancy and breastfeeding. Patient with diabetes mellitus. Patients with a history of hypersensitivity or adverse reactions associated with (BTX_A). Recent BTA administration 6 months before the study. Any subject complaining of psychiatric disorders or neurological disorders such as myasthenia gravis.
Sites / Locations
- Faculty of physical therapyRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Botulinum Toxin Type a Iontophoresis for Postburn Hypertrophic Scar
Traditional physical therapy for postburn hypertrophic scar
The study group includes 38 postburn hypertrophic scar patients l receiving Botox iontophoresis once monthly for 3 months; in addition to their physical therapy program (Stretching exercises, Pressure Therapy and Massage) 2 sessions per week for 3 months. Botulinum toxin type A (Botox Allergan ®, Irvine, CA, USA) is used. 100 U vacuum-dried powder in a single-use vial for reconstitution diluted in 2 mL of sterile, preservative-free 0.9% saline to constitute a solution at a concentration of 4 U/0.1 mL) is being administered once a month for a total period of three months. The dose will be adjusted to 2.5 U/cm2 of the scar. The dose shouldn't exceed 100 units per session.
This group includes 38 patients with postburn hypertrophic scar who will receive the traditional PT (deep friction massage, stretching and pressure therapy).