A Comparison of Three Commercial Oral Rehydration Solutions Consumed After Extra-cellular Dehydration
Fluid Balance Outcomes
About this trial
This is an interventional basic science trial for Fluid Balance Outcomes
Eligibility Criteria
Inclusion Criteria: 18-45 years of age male or female good health Exclusion Criteria: Gastrointestinal, cardiovascular or renal conditions; other health conditions that might influence the study outcomes. Medication use (e.g. anti-biotics, diuretics, NSAIDS etc.) that might influence the study outcomes or interact with furosemide. Allergy to sulfonamides (sulfa drugs). Smoking (including vaping) Amenorrhoeic females Any high-level/elite athlete, or aspiring high level athlete, where drug testing/regulations are carried out and regulations need to be followed (furosemide is prohibited in sport as it is used as a masking agent).
Sites / Locations
- Loughborough University
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Experimental
Commercially Available Oral Rehydration Solution A
Commercially Available Oral Rehydration Solution B
Commercially Available Oral Rehydration Solution C
A commercially available oral rehydration solution (~2.8% carbohydrate, ~45 mmol/L sodium, ~20 mmol/L potassium, 34 mmol/L chloride)
A commercially available oral rehydration solution (~0.1% carbohydrate, ~2% amino acids (protein), ~67 mmol/L sodium, ~20 mmol/L potassium, 30 mmol/L chloride)
A commercially available oral rehydration solution (~2.2% carbohydrate, ~45 mmol/L sodium, ~20 mmol/L potassium)