Dietary Intervention to Reduce Metabolic Endotoxemia
Endotoxemia, Intestinal Microbiota, Dietary Habits
About this trial
This is an interventional prevention trial for Endotoxemia focused on measuring Metabolic endotoxemia, Lipopolysaccharide binding protein, Dietary inflammatory index, Planetary health diet
Eligibility Criteria
Inclusion Criteria: Obesity according to body mass index: ≥ 30 kg/m2 Willingness to participate and sign the consent form. Willingness to follow the dietary recommendations of the protocol. Have access to the internet and an electronic device. Exclusion Criteria: Clinically diagnosed with hyperglycemia, hypertension, cardiovascular disease, renal disease, hepatic disease, immunosuppression, or another metabolic disease. Being under a dietary restriction regimen or pharmacological treatment to lose weight. Consuming dietary supplements for at least six months (vitamins, fatty acids, probiotics, prebiotics). Being under treatment with antibiotics or anti-inflammatory drugs in the last three months. Having bariatric surgery. Being pregnant or lactating. Present gastrointestinal disease Present Coronavirus disease (COVID-19) symptoms Develop diseases that affect body weight Becoming pregnant Withdrawal of informed consent.
Sites / Locations
- Universidad Vizcaya de las AméricasRecruiting
- Centro de Investigación en Alimentación y DesarrolloRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Low-inflammatory and environmentally friendly dietary strategy (AIA-D)
General healthy diet recommendations (CONV-D).
The environmentally friendly dietary strategy (AIA-D) designed based on the planetary health diet recommendations translated to the regional context and includes nutrients related to anti-inflammatory responses
The active comparator CONV-D is based on the general healthy diet recommendations