Protein Turnover in Healthy and Overuse-diseased Tendon
Patella; Tendinitis
About this trial
This is an interventional basic science trial for Patella; Tendinitis
Eligibility Criteria
Inclusion Criteria: Physical active men and women Body mass index 18,5 - 30 kg/m2 Inclusion Criteria for the chronic tendinopathy group: Debut of symptom > 90 days prior to inclusion. Subjective activity related pain in patella tendon. Clinical symptoms of patella tendinopathy. Ultrasound verification of at least 1 in three of the following: Enchanced anterior-posterior diameter, increased Doppler signal and/or a hypoechoic area in the diseased part of the tendon. Exclusion Criteria for all participants: Former knee surgery or injuries to the patella tendon. Local injection of corticosteroids within 12 months. Medication that affects protein synthesis in tendon tissue. Former/current use of anabolic steroids or growth hormone. Smoking Known rheumatoid disease or diabetes. Former participation in trials using deuterated water and 15N tracers. Treatment for patella tendinopathy within 3 months.
Sites / Locations
- Institute of Sports Medicine CopenhagenRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Chronic tendinopathy patients
Healthy controls