StuDy AimED at Increasing AlCohol AbsTinEnce
Alcohol Use Disorder
About this trial
This is an interventional treatment trial for Alcohol Use Disorder
Eligibility Criteria
Inclusion Criteria: Male and female young adults aged 18-24 yr English-speaking Current alcohol use greater or equal to 1 day/week via phone screening, and meet criteria for (past year) mild, moderate or severe AUD on the AUDIT and AUDADIS surveys. Completion of written informed consent Baseline screening study visit. Exclusion Criteria: Participation in past 6 mo. in AUD or substance use treatment Current use of medications used to treat AUD (e.g., naltrexone) Lifetime DSM-5 diagnosis of schizophrenia, bipolar disorder, or any psychotic disorder. Current use of psychoactive drugs, determined by positive drug toxicology screen Conditions (e.g., tic disorder) that would interfere with psychophysiological indices of reward functioning Pregnancy or intention to become pregnant Additional exclusion criteria pertaining to fMRI scan in R00 phase only: a) bodily ferrous metals (e.g., aneurysm clips, shrapnel/retained particles) or b) claustrophobia, inability to tolerate small enclosed spaces.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Other
Other
Treatment group
Control group
For the R00 phase: CM-PST treatment group will receive CM-PST intervention, which will consist of 8 sessions total, delivered remotely via Zoom videoconferences in individual sessions over 12 weeks. The first 4 sessions will be delivered weekly, and the remaining 4 sessions every other week. CM-PST will teach participants problem-solving skills using a structured 5-step method. In addition, participants will receive incentives for alcohol abstinence and submission of urine samples twice/wk. K99 phase participants will also receive CM-PST intervention.
For the R00 phase: Participants in CM-only control will receive incentives for alcohol abstinence and submission of urine samples twice/wk. Participant incentives will start at a $10 gift card, with a $5 increase each subsequent measurement point on which alcohol is not detected or reported, to a maximum of $25, but no gift card on days when alcohol use is detected or reported, and the gift card reinforcer value will be re-set to $10.