Single-cell Transcriptome Identification of UV- and Visible-light-induced Genes in Human Melanocytes in Vivo (melatrans)
Skin Diseases
About this trial
This is an interventional other trial for Skin Diseases
Eligibility Criteria
Inclusion Criteria: Subjects of male sex, phototype III (on the Fitzpatrick scale from I to VI), age 25+5 years and of similar build (body mass index between 20 and 28). - Subject not having been exposed to natural or artificial sunlight in the regions studied for at least 3 months, and not presenting a tan at this level. - Subject showing no skin pathology, scar, or tattoo, in the regions studied. - Subjects who agreed to have a blood test with HIV, hepatitis B and C testing. - Subjects affiliated to a social security scheme - Subjects informed of the aims and nature of the test and having signed a written consent before the start of the study. - Subjects having undergone a general clinical examination attesting to their ability to participate in the study. Exclusion Criteria: - Subjects with a history of dystrophic scarring, particularly of keloids. The preliminary medical examination will endeavor to examine the possible scars of the subject. - Subjects with a dermatological condition that may interfere with assessments. - Subjects with a history of skin cancer. - Subjects having had recourse during the fifteen days preceding the test to systemic or local therapies that risk interfering with the results of the study (eg: corticosteroids, anti-histamines, non-steroidal anti-inflammatory drugs). - Subjects with positive HIV, Hepatitis B (HBSAg surface antigen) and Hepatitis C antibody tests, therefore accepting a blood sample for HIV, hepatitis B and C testing. - Subjects with a history of illness likely, according to the investigator, to put them at risk as a result of the study, in particular photodermatosis, photoaggravated pathologies, atopic dermatitis, chronic urticaria, actinic keratoses, etc. - Subjects allergic to xylocaine adrenaline - Subjects who regularly use sedatives, tranquilizers or other medications known to be photosensitizers - Subjects who have already participated in a pharmacological
Sites / Locations
- CHU de Nice - Hôpital de l'ArchetRecruiting
Arms of the Study
Arm 1
Other
Voluntary