Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals
Primary Purpose
Septic Arthritis
Status
Not yet recruiting
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Surgery of Drainage of septic hip arthritis
Sponsored by
About this trial
This is an interventional treatment trial for Septic Arthritis
Eligibility Criteria
Inclusion Criteria: - Children younger than 14 years old presented with septic hip arthritis only or by bilateral septic hip arthritis in Assiut University Hospitals Exclusion Criteria: 1-patients with Tuberculous arthritis 2-patients whose parents refuse to participate in the study
Sites / Locations
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Children presented with septic hip arthritis in Assiut University Hospitals
Arm Description
Surgery of Drainage of pus in septic hip arthritis
Outcomes
Primary Outcome Measures
Modified Moon's criteria for outcome assessment of hip function
Secondary Outcome Measures
Detection of Complications
Complications such as limb-lenght discrepancy , Avascular necrosis of the femoral head and hip destruction will be documented
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT05780697
Brief Title
Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals
Official Title
Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals
Study Type
Interventional
2. Study Status
Record Verification Date
March 2023
Overall Recruitment Status
Not yet recruiting
Study Start Date
March 2023 (Anticipated)
Primary Completion Date
March 2024 (Anticipated)
Study Completion Date
March 2025 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Assiut University
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
5. Study Description
Brief Summary
Detect short term results of pediatric septic hip arthritis and its risk factors
Detailed Description
Septic arthritis of the hip is a true orthopedic emergency(1). In developed countries, the incidence of acute bacterial septic arthritis is estimated to be 4 to 10 per 100,000 children (2).It is caused by many microorganisms. Staph aureus is most common in children over 2 years of age . Staph aureus is gram-positive cocci in clusters and most common in nosocomial infections of neonates(3-4).Group B streptococcus is most common in neonates with community-acquired infection and exposed during transvaginal delivery(5).Neisseria gonorrhoeae is gram-negative diplococci and most common in adolescents.when the causative Organism is Neisseria gonorrhoeae ,patients usually have a preceding migratory polyarthralgia,multiple joint involvement and small red papules(6-7).Group A beta-hemolytic streptococcus is most common organism following varicella infection.HACEK organisms (Haeophilus,Actinobacillus,Cardiobacterium,Eikenella,and Kingella fastidious) are less common causative organisms(8-9).Early diagnosis and accurate treatment is key in avoiding complications such as joint destruction,joint dislocation , ankylosis, growth arrest or spread of infection leading to osteomyelitis , pelvic abscess or nerve lesions.. Treatment is started without delay after synovial fluid and blood samples have been obtained. The classical presentation of septic hip arthritis in children is a combination of a painful hip joint with limited range of motion, fever, malaise and inability to bear weight on the affected limb. Misdiagnosis or inappropriate treatment of acute septic arthritis of the hip in children can result in devastating damage of the joint and possible lifelong disability. Open arthrotomy , drainage and thorough irrigation of the joint is considered the standard treatment for septic arthritis of the hip.Empiric antibiotic treatment primarily targets S. aureus and takes into account its resistance to antibiotics(10-11). So,we want to detect short term results of pediatric septic hip arthritis at Assiut University Hospitals
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Septic Arthritis
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
50 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
Children presented with septic hip arthritis in Assiut University Hospitals
Arm Type
Experimental
Arm Description
Surgery of Drainage of pus in septic hip arthritis
Intervention Type
Procedure
Intervention Name(s)
Surgery of Drainage of septic hip arthritis
Intervention Description
Surgery for septic hip arthritis by anterior or lateral approach and inspection of femoral head
Primary Outcome Measure Information:
Title
Modified Moon's criteria for outcome assessment of hip function
Time Frame
Baseline
Secondary Outcome Measure Information:
Title
Detection of Complications
Description
Complications such as limb-lenght discrepancy , Avascular necrosis of the femoral head and hip destruction will be documented
Time Frame
Baseline
10. Eligibility
Sex
All
Minimum Age & Unit of Time
1 Day
Maximum Age & Unit of Time
14 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
- Children younger than 14 years old presented with septic hip arthritis only or by bilateral septic hip arthritis in Assiut University Hospitals
Exclusion Criteria:
1-patients with Tuberculous arthritis 2-patients whose parents refuse to participate in the study
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Beshoy Elkes Abram, Resident Dr
Phone
01284144493
Email
Beshoelghalban_2010@yahoo.com
12. IPD Sharing Statement
Plan to Share IPD
No
Citations:
PubMed Identifier
6630490
Citation
Fabry G, Meire E. Septic arthritis of the hip in children: poor results after late and inadequate treatment. J Pediatr Orthop. 1983 Sep;3(4):461-6. doi: 10.1097/01241398-198309000-00008.
Results Reference
background
PubMed Identifier
25553604
Citation
Ilharreborde B. Sequelae of pediatric osteoarticular infection. Orthop Traumatol Surg Res. 2015 Feb;101(1 Suppl):S129-37. doi: 10.1016/j.otsr.2014.07.029. Epub 2014 Dec 29.
Results Reference
background
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Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals
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