The Effectiveness and Safety of Ultrasound Elastography Guided Pleural Biopsy in the Differential Diagnosis of Benign and Malignant Pleural Effusion
Pleural Effusion
About this trial
This is an interventional diagnostic trial for Pleural Effusion
Eligibility Criteria
Inclusion Criteria: Patients with unexplained pleural effusion (patients with pleural effusion with negative aspiration) Sign the informed consent form The patient must have chest CT, biochemical examination of pleural fluid, cytological examination of pleural fluid and other data before operation Exclusion Criteria: The cytological examination of pleural fluid indicates "highly suspicious" patients (unless the cytological examination results of patients are inconsistent with clinical manifestations and CT examination). The pleural fluid cytology proved to be malignant. Patients with severe pleural adhesion who cannot undergo medical thoracoscopic examination will not be randomly selected, and elastic ultrasound-guided biopsy can be performed after informed consent, as a subgroup of population analysis. Those who cannot tolerate closed pleural biopsy due to severe cardiopulmonary dysfunction and poor general condition Coagulation dysfunction. Leakage. The age is less than 18 years old. The pleural fluid cytology proved to be malignant. Patients with severe pleural adhesion who cannot undergo medical thoracoscopic examination will not be randomly selected, and elastic ultrasound-guided biopsy can be performed after informed consent, as a subgroup of population analysis. Those who cannot tolerate closed pleural biopsy due to severe cardiopulmonary dysfunction and poor general condition Coagulation dysfunction. transudate The age is less than 18 years old.
Sites / Locations
- Anhui Chest HospitalRecruiting
- China-Japan Friendship HospitalRecruiting
- Gui Zhou Provincial People's HospitalRecruiting
- the Second Xiangya Hospital of Central South UniversityRecruiting
- the First Affiliated Hospital of Nanchang UniversityRecruiting
- the First Hospital of China Medical UniversityRecruiting
- The Tenth People's Hospital of ShenyangRecruiting
- the First People's Hospital of Yunnan ProvienceRecruiting
- the Second Affiliated Hospital Zhejiang University School of MedicineRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Ultrasound elastography guided pleural biopsy group
Traditional ultrasound-guided pleural biopsy group