Neural Respiratory Drive of Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
About this trial
This is an interventional basic science trial for Chronic Obstructive Pulmonary Disease focused on measuring neural respiratory drive, chronic obstructive pulmonary disease
Eligibility Criteria
Inclusion Criteria: The diagnosis of COPD was made according to the global initiative for chronic obstructive lung disease (GOLD) guideline. - Exclusion Criteria: (1) Malignancy (2)Severe cardiovascular diseases (3)Neuromuscular and chest wall deformity (4) Cardiovascular instability (hypotension, arrhythmias, myocardial infarction) (5) Change in mental status; uncooperative patients (6) Extreme obesity (7)renal failure and severe blood electrolyte disturbances (8) Asthma-
Sites / Locations
- 1State Key Laboratory of Respiratory Disease, National clinical research center for respiratory disease, Guangzhou Institute of respiratory health. 2The First Affiliated Hospital of Guangzhou Medical UniversityRecruiting
Arms of the Study
Arm 1
Experimental
bronchodilators
compound ipratropium bromide solution (3mg salbutamol and 500μg ipratropium, Boehringer Ingelheim Limited, Germany)