Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility
Male Infertility, Asthenozoospermia, Oligoasthenozoospermia
About this trial
This is an interventional treatment trial for Male Infertility
Eligibility Criteria
Inclusion Criteria: The participants must meet all following criteria at the time of randomization to be eligible for recruitment : Study participants met the diagnostic criteria for male infertility 1)inability to have a child after at least 1 year of marriage with regular sexual life and without using any preventive methods 2)normal fertile female partner Study participants met the diagnostic criteria for AZS or OA For AZS: sperm concentration ≥15 × 106/ mL PR <32% For OA: sperm concentration <15 × 106/ mL PR <32% (3) Study participants met the TCM diagnosis criteria for kidney deficiency and blood stasis (4) Men aged 22 to 45 years (5) The participants signed informed consent forms Exclusion Criteria: The trial exclusion criteria included any of the following: infertility is caused by the inability to complete sexual intercourse, including but not limited to erectile dysfunction or ejaculatory disorders with infertility caused by organic lesions of the reproductive system with reproductive system infection, such as chlamydia trachomatis or mycoplasma infection with palpable varicocele with abnormal and clinical significance of sex hormone (FSH, LH, T) complicated with liver and kidney dysfunction, severe basic diseases such as diabetes, cardiovascular and cerebrovascular diseases, mental diseases, malignant tumors, or serious organic diseases with a history of allergy to any medicine or ingredients used in this study receive other relevant treatment for the disease 2 weeks before treatment
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Experimental group
Control group
LGYY+ WZYZ mimetic
WZYZ + LGYY mimetic