Automated Insulin Delivery in Type 1 Diabetes Complicated by Gastroparesis (AIDgastro)
Gastroparesis, Type 1 Diabetes
About this trial
This is an interventional treatment trial for Gastroparesis
Eligibility Criteria
Inclusion Criteria: Aged 18 years of age or older Type 1 diabetes confirmed on the basis of clinical features Type 1 diabetes for greater than 1 year On an intensified insulin regimen with multiple dose injection or insulin pump for > 3 months HbA1c >7.5% (58mmol/mol) (or %TIR 3.9-10mmol/L <52% for participants already using a continuous glucose sensor) Gastroparesis Cardinal Symptom Index (GCSI) ≥ 18 or evidence of delayed gastric emptying on nuclear medicine gastric emptying study Exclusion Criteria: Enrolled in other clinical trials Estimated glomerular filtration rate of ≤30ml/min Pregnant or planning pregnancy Have active malignancy or under investigation for malignancy Severe visual impairment Reduced manual dexterity Use of any automated insulin delivery system Unable to participate due to other factors, as assessed by the Chief Investigator
Sites / Locations
- Imperial College London and Imperial College Healthcare NHS TrustRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Hybrid Automated Insulin Delivery
Standard care
The intervention is the Medtronic 780G Hybrid Automated Insulin Delivery system
The control is Standard Care with real-time CGM